반응 #2097

ord-37d510efe3de46df8fb8264294561f22

반응 방정식

CCCn1c(=O)c2[nH]cnc2n(CCC)c1=O
1,3-dipropylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate
→
CCCn1c(=O)c2c(ncn2CCCP(=O)(OCC)OCC)n(CCC)c1=O
Diethyl [3-(1,3-dipropylxanthin-7-yl)propyl]phosphonate

반응물

CCCn1c(=O)c2[nH]cnc2n(CCC)c1=O
1,3-dipropylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타chromatographed on silica gel (eluent: ethyl acetate/methanol 20:1)

실험 절차

The title substance was prepared from 1,3-dipropylxanthine and diethyl 3-bromopropanephosphonate analogously to Example 1 and chromatographed on silica gel (eluent: ethyl acetate/methanol 20:1).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05728686uspto-grants-1998_03