반응 #2088527

ord-4de9f2e1adb446188c64565d901fa678

반응 방정식

O=CN1C(=O)c2ccccc2S1(=O)=O
O=CN1C(=O)c2ccccc2S1
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2
CC[Si](CC)CC
CC[Si](CC)CC
→
CC(C)(C)OC(=O)N1CCc2cc(C=O)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2

반응물

O=CN1C(=O)c2ccccc2S1(=O)=O
O=CN1C(=O)c2ccccc2S1(=O)=O
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(O
CC[Si](CC)CC
CC[Si](CC)CC

시약

CC(=O)[O][Pd][O]C(C)=O
Pd(OAc)2
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
CCN(C(C)C)C(C)C
DIPEA
c1ccc(P(C[C@@H]2C[C@H](P(c3ccccc3)c3ccccc3)CN2)c2ccccc2)cc1
PPM

용매

CN(C)C=O
DMF

반응 조건

온도
80°CELSIUS

출처

DOI: 10.1038/s4155739k HTE dataset from Pfizer