반응 #2080903

ord-e8a30dd8fc7440608e7682ea3b084b83

반응 방정식

CC(=O)O[C@H]1[C@H](OC(C)=O)CSC(Br)[C@@H]1OC(C)=O
2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide
Cc1nc2cc(O)ccc2s1
2-methyl-5-hydroxybenzothiazole
→
CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)CS[C@H]1Oc1ccc2sc(C)nc2c1
desired product
수율 6.0%
CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)CS[C@H]1Oc1ccc2sc(C)nc2c1
2-methyl-5-benzothiazolyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside
수율 6.0%

반응물

CC(=O)O[C@H]1[C@H](OC(C)=O)CSC(Br)[C@@H]1OC(C)=O
2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide
Cc1nc2cc(O)ccc2s1
2-methyl-5-hydroxybenzothiazole

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

By carrying out the process in a manner similar to example 7, starting from 2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide and 2-methyl-5-hydroxybenzothiazole, the desired product is obtained in the form of white crystals with a yield of 6%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07652032B2uspto-grants-2010_01