반응 #2069924

반응 방정식

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

용매

chloroform

반응 조건

후처리

1. 1
   온도In the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   농축The reaction mixture is concentrated to dryness
4. 4
   기타the resulting, reddish-white solid is recrystallized from hexane

실험 절차

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

출처