반응 #2018242

ord-68f0c524350444f893a26f88b429c412

반응 방정식

CC(C)(C)OC(=O)/C=C/c1cc[nH]c1
compound D1
CC(C)(C)OC(=O)/C=C/c1cc[nH]c1
(E)-3-(1H-pyrrol-3-yl)acrylic acid tert-butyl ester
O=S(=O)(Cl)c1ccc(Br)cc1
4-bromo-benzenesulfonyl chloride
→
CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(Br)cc2)c1
title compound
CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(Br)cc2)c1
(E)-3-[1-(4-Bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl ester

반응물

CC(C)(C)OC(=O)/C=C/c1cc[nH]c1
compound D1
CC(C)(C)OC(=O)/C=C/c1cc[nH]c1
(E)-3-(1H-pyrrol-3-yl)acrylic acid tert-butyl ester
O=S(=O)(Cl)c1ccc(Br)cc1
4-bromo-benzenesulfonyl chloride

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Starting from compound D1 and 4-bromo-benzenesulfonyl chloride the title compound can be obtained analogously as described for compound D2.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08188138B2uspto-grants-2012_05