반응 #2006432

반응 방정식

4-nitro-2,2′-bipyridyl-N-oxide

acetyl bromide

→

4-bromo-2,2′-bipyridyl-N-oxide

수율 95.0%

용매

acetic acid

반응 조건

후처리

1. 1
   온도The yellow mixture was refluxed for 1.5 h
2. 2
   기타The resulting light yellow solid was sufficiently pure enough for the next step without further purification

실험 절차

To 4-nitro-2,2′-bipyridyl-N-oxide (Wenkert, D.; Woodward, R. B. J. Org. chem. 48,283 (1983)) (5 g) dissolved in 30 mL acetic acid in a 100 ml round bottom flask was added 16 mL acetyl bromide. The yellow mixture was refluxed for 1.5 h and then rotovaporated to dryness. The resulting light yellow solid was sufficiently pure enough for the next step without further purification. Yield: 95%

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