반응 #1994252

반응 방정식

water

carbazole

sodium hydroxide

allylbromide

→

N-Allylcarbazole

용매

dimethylsulfoxide

반응 조건

후처리

1. 1
   추출extracted with ethyl acetate
2. 2
   세척The ethyl acetate layer was washed with water
3. 3
   농축concentrated
4. 4
   기타The crude product was purified

실험 절차

A mixture of 10.85 g (65.0 mmol) of carbazole, 2.60 g (65.0 mmol) of sodium hydroxide and 6.1 mL (72.0 mmol) of allylbromide in 100 mL dimethylsulfoxide was heated to 60° C. for 5 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate layer was washed with water and then concentrated. The crude product was purified using column chromatography (silica, 1:4 dichloromethane:hexane). Yield: 9.85 g (73%).

출처