반응 #1985944
ord-cf38f96581534566aa8c89c9a242ad2a
반응 방정식
methyl 5-acetoxy-2-formyl-4-methoxyhydrocinnamate
imidazole
tert-butylchlorodimethylsilane
→
desired product
Methyl 5-Acetoxy-2-tert-butyldimethylsilyloxymethyl-4-methoxyhydrocinnamate
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척the organic layer washed with water, brine
- 2건조dried over magnesium sulfate
- 3여과filtered
- 4농축concentrated in vacuo
실험 절차
To a solution of methyl 5-acetoxy-2-formyl-4-methoxyhydrocinnamate (3.31 g) and imidazole (2.42 g) in methylene chloride (25 ml) is added a solution of tert-butylchlorodimethylsilane (2.73 g) in methylene chloride (25 ml). The mixture is stirred at room temperature for about 60 minutes, diluted with ether and water, and the organic layer washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.