반응 #1985943
ord-d02b5e2cb1c64e93bd705cc8158c50d1
반응 방정식
methyl 5-acetoxy-2-formyl-4-methoxycinnamate
→
desired product
Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과filtered
- 2농축The filtrate is concentrated in vacuo
- 3기타the residue purified by HPLC
- 4세척eluting 50% ethyl acetate in hexanes
실험 절차
A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.