반응 #1985940

반응 방정식

vanillin

triethylamine

acetic anhydride

→

desired product

4-Acetoxy-3-methoxybenzaldehyde

용매

ether

methylene chloride

반응 조건

후처리

1. 1
   세척the solution washed with water, brine
2. 2
   건조dried over magnesium sulfate
3. 3
   여과filtered
4. 4
   농축concentrated in vacuo

실험 절차

A solution of vanillin (60.8 g), triethylamine (60 ml), acetic anhydride (44 ml), and 4-dimethylaminopyridine (1.0 g) in methylene chloride (800 ml) is stirred at room temperature for about 30 minues, and the volume then reduced by 50% in vacuo. The residue is diluted with ether and the solution washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

출처