반응 #1978501

반응 방정식

sodium acetate

4-methyl-3-nitrobenzaldehyde

hydroxylamine hydrochloride

ethanol

→

5-hydroxyiminomethyl-2-methylnitrobenzene

수율 84.6%

용매

water

water

반응 조건

후처리

1. 1
   추출followed by extraction with ethyl acetate
2. 2
   건조The organic layer was dried over anhydrous sodium sulfate
3. 3
   농축concentrated under reduced pressure

실험 절차

To a mixture of 3.00 g of 4-methyl-3-nitrobenzaldehyde, 1.64 g of hydroxylamine hydrochloride, 30 ml of ethanol and 15 ml of water was added 2.24 g of sodium acetate at room temperature, followed by stirring at room temperature for 1 hour. The reaction mixture was added to water, followed by extraction with ethyl acetate. The organic layer was dried over anhydrous sodium sulfate and then concentrated under reduced pressure to obtain 2.77 g of 5-hydroxyiminomethyl-2-methylnitrobenzene. 5-Hydroxyiminomethyl-2-methylnitrobenzene

출처