반응 #1973928

ord-2c5e79c602a84d9fa0caec80d5c30337

반응 방정식

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)O
2-(12-phthalimido dodecyl)propane dioic acid
수율 100.0%

반응물

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid

시약

없음

용매

ClCCl
dichloromethane

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08501199B2uspto-grants-2013_08