반응 #1972698

반응 방정식

2,5-Dichloroanisole

2,4,5-trichloroaniline

→

4-Methoxy-2,2',4',5,5'-pentachlorobiphenyl

반응 조건

후처리

1. 1
   기타The excess dichloroanisole was removed by distillation
2. 2
   여과the residue was then filtered through silica gel (heptane eluent)
3. 3
   기타further purified [Chromatotron®, 4 mm silica gel, hexane, 20 mL/min]

실험 절차

4-Methoxy-2,2',4',5,5'-pentachlorobiphenyl was prepared from 2,5-Dichloroanisole (35 g, 200 mmol) and 2,4,5-trichloroaniline (2.95 g, 15 mmol) according to the procedure in Example 2A. The excess dichloroanisole was removed by distillation and the residue was then filtered through silica gel (heptane eluent) and further purified [Chromatotron®, 4 mm silica gel, hexane, 20 mL/min] to give the product (980 mg). Mass spectrum: m/z at 354 for C13H7Cl5O.

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