반응 #1957258
ord-1b98692b2a9e4a6ab020cb0d0cb62240
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타16-Bromohexadecanoic acid was prepared
- 2온도Upon cooling
- 3여과It was filtered out
- 4세척washed with 3×100 ml of cold water
- 5기타Material was purified by recrystalization from n-hexane
- 6여과filtered out
- 7기타dried on high vacuum
실험 절차
16-Bromohexadecanoic acid was prepared by refluxing for 48 hrs 5.0 gr (18.35 mmole) of 16-hydroxyhexadecanoic acid in 24 ml of 1:1 v/v mixture of HBr (48% aqueous solution) and glacial acetic acid. Upon cooling, crude product was solidified inside the reaction vessel. It was filtered out and washed with 3×100 ml of cold water. Material was purified by recrystalization from n-hexane, filtered out and dried on high vacuum. 6.1 gr (99% yield) of the desired product were obtained.