반응 #1937646

반응 방정식

1-(7-methoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine

1-bromo-4-(trifluoromethyl)benzene

→

title compound

수율 55.1%

1-(7-Methoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-4-[4-(trifluoromethyl)phenyl]piperazine

수율 55.1%

반응 조건

실험 절차

By using 1-(7-methoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine (552 mg, 2.0 mmol) synthesized in Reference example 88 and 1-bromo-4-(trifluoromethyl)benzene (900 mg, 4.0 mmol), the reaction was carried out in the same manner as Example 23 to synthesize the title compound 463 mg (yield 55%). Melting point was 142 to 145° C. (ethanol-water).

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