반응 #1929023

반응 방정식

3-Nitrophenyl benzoate

tin (II) chloride dihydrate

sodium carbonate

→

3-aminophenyl benzoate

수율 100.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타The reaction crude
2. 2
   온도to cool to room temperature
3. 3
   추출The crude material was extracted with dichloromethane (3×50 mL), magnesium sulfate
4. 4
   workup.ADDITIONwas added to the organic phase
5. 5
   여과filtered
6. 6
   기타the solvent was removed under reduced pressure

실험 절차

3-Nitrophenyl benzoate (2.7080 g, 11.144 mmol) and tin (II) chloride dihydrate (12.564 g, 55.720 mmol) were dissolved in 60 mL of ethanol and heated at 100° C. for 1 hour. The reaction crude was allowed to cool to room temperature, and an aqueous solution of sodium carbonate was added until pH 8. The crude material was extracted with dichloromethane (3×50 mL), magnesium sulfate was added to the organic phase, filtered and the solvent was removed under reduced pressure, thus affording 2.374 g (11.143 mmol, yield=100%) of 3-aminophenyl benzoate.

출처