반응 #1885009

반응 방정식

mono nitro-benzothiophene-2-sulfonate

silver carbonate

hexane ethyl acetate

→

silver mono nitro-benzo[b]thiophene-2-sulfonate

수율 98.2%

용매

acetonitrile

water

반응 조건

후처리

1. 1
   여과The mixture was filtered through half an inch of Celite°
2. 2
   세척the solid was washed with 3×40 mL acetonitrile
3. 3
   기타organic solvent was removed via rotary evaporator to dryness and thus afforded 0.668 g of viscous solid with a yield of 98.2%
4. 4
   기타The resulting compound was not purified for further reactions

실험 절차

To a solution of mono nitro-benzothiophene-2-sulfonate (0.5177 g, 1.86 mmol) in 50 mL of acetonitrile and 1 mL of water was added silver carbonate (0.6169 g, 2.24 mmol) in portions in darkness. The resulting suspension was stirred overnight for 9 days, until no starting material is shown on the thin layer chromatography with an eluent of hexane/ethyl acetate (1:4). The mixture was filtered through half an inch of Celite° and the solid was washed with 3×40 mL acetonitrile. The organic filtrate was combined and organic solvent was removed via rotary evaporator to dryness and thus afforded 0.668 g of viscous solid with a yield of 98.2%. The resulting compound was not purified for further reactions.

출처