반응 #1869186

반응 방정식

4-amino-benzonitrile

2,2-dimethyl-[1,3]dioxane-4,6-dione

trimethylorthoformate

→

solid

수율 97.0%

4-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-benzonitrile

수율 97.0%

용매

ethanol

반응 조건

후처리

1. 1
   온도was refluxed for 3 hours
2. 2
   온도After cooling the solid
3. 3
   여과was filtered off
4. 4
   세척washed with ethanol and air
5. 5
   기타dried

실험 절차

A mixture of 4-amino-benzonitrile (12.5 g, 0.106 mol), 2,2-dimethyl-[1,3]dioxane-4,6-dione (18.3 g, 0.127 mol) and trimethylorthoformate (16 ml) in ethanol (100 ml) was refluxed for 3 hours. After cooling the solid was filtered off, washed with ethanol and air dried. The product was obtained as an off-white solid (27.9 g, 97%).

출처