반응 #1818824

ord-645e3c7bf23e44ca89ff93185df59085

반응 방정식

O=C(O)C1=CC2=CCCC=C2Sc2c1ccc1c2C(=O)CC1
1-oxo2,3,9,10-tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid
O=C(O)c1ccc2c(c1)Sc1ccc3c(c1CC2)C(=O)CC3
1-oxo2,3,11,12-tetrahydro-1H-benzo[b]indeno[4,5-f]thiepin-8-carboxylic acid
O=C(O)C1=CC2=CCCC=C2Sc2c1ccc1c2CCC1
title compound
O=C(O)C1=CC2=CCCC=C2Sc2c1ccc1c2CCC1
2,3,9,10-Tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도heating
  2. 2
    온도under reflux for 9 hours instead of 3 hours

실험 절차

Substituting an equivalent amount of 1-oxo2,3,9,10-tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid in Example 41 in place of 1-oxo2,3,11,12-tetrahydro-1H-benzo[b]indeno[4,5-f]thiepin-8-carboxylic acid and heating under reflux for 9 hours instead of 3 hours yielded the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04622403uspto-grants-1986_11