반응 #1817105

반응 방정식

1-chloro-4-acetoxynonane

ethyl 7-[N-(4-acetoxy-8,8-dimethylnonyl)cyanamido]heptanoate

1-chloro-4-acetoxy-8,8-dimethylnonane

→

7-[1-(4-hydroxy-8,8-dimethylnonyl)ureido]heptanoic acid

7-[1-(4(R)-hydroxy-2-nonynyl)ureido]heptanoic acid

7-[N-(4-hydroxy-8,8-dimethylnonyl)cyanamido]-heptanoic acid

7-[N-(4-(R)-hydroxy-2-nonynyl)cyanamido]heptanoic acid

반응 조건

후처리

1. 1
   기타The synthesis of this compound

실험 절차

The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-chloro-4-acetoxy-8,8-dimethylnonane (Example D). The product of Step A is thus ethyl 7-[N-(4-acetoxy-8,8-dimethylnonyl)cyanamido]heptanoate. The subsequent steps yield 7-[N-(4-hydroxy-8,8-dimethylnonyl)cyanamido]-heptanoic acid (B) and 7-[1-(4-hydroxy-8,8-dimethylnonyl)ureido]heptanoic acid (C).

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