반응 #1811

반응 방정식

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

용매

Methanol

반응 조건

후처리

1. 1
   농축The mixture was concentrated
2. 2
   기타the residue was chromatographed (silica gel, 5% methanol/dichloromethane)

실험 절차

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

출처