반응 #1810803

반응 방정식

(4-amino-cyclohexyl)-carbamic acid tert-butyl ester

ethoxycarbonyl-isothiocyanat

→

[trans-4-(3-Ethoxycarbonyl-thioureido)cyclohexyl]carbamic acid tert-butyl ester

반응 조건

후처리

1. 1
   기타the mixture obtained
2. 2
   기타The precipitate formed
3. 3
   여과is filtered
4. 4
   세척washed with diethylether

실험 절차

To a solution of 1.10 g of (4-amino-cyclohexyl)-carbamic acid tert-butyl ester in 25 ml of EtAc 0.58 ml of ethoxycarbonyl-isothiocyanat are added and the mixture obtained is stirred at RT. The precipitate formed is filtered and washed with diethylether. [trans-4-(3-Ethoxycarbonyl-thioureido)cyclohexyl]carbamic acid tert-butyl ester is obtained.

출처