반응 #1803428

ord-cb53add2a8e34202a17e9df12cce7574

반응 방정식

O=C(O)CSc1nc2ccccc2s1
2-(benzo[d]thiazol-2-ylthio)acetic acid
Fc1ccc2c(c1)NCC2
6-fluoroindoline
O=C(CSc1nc2ccccc2s1)N1CCc2ccc(F)cc21
43
수율 70.0%
O=C(CSc1nc2ccccc2s1)N1CCc2ccc(F)cc21
2-(Benzothiazol-2-ylsulfanyl)-1-(6-fluoro-2,3-dihydro-indol-1-yl)-ethanone
수율 70.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The title compound was synthesized

실험 절차

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 6-fluoroindoline to yield 43 as a white solid (70%): MS m/z: 345 (M+H)+. Anal. Calcd. For, C17H13N2FOS2: C, 59.28; H, 3.80; N, 8.13; S, 18.62; F, 5.52. Found: C, 59.51; H, 3.85; N, 8.13; S, 18.73; F, 5.37.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07803790B2uspto-grants-2010_09