반응 #1781646

ord-01fd56d0e4fe477e9fbb8646bd63e232

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The methyl ester from Step I (565 mg, 1.13 mmol) was acylated with trans-4-methylcyclohexyl carboxylic acid chloride as previously described (example 11, step II) to give 41 mg (27%) of 5-cyclohex-1-enyl-3-[(trans-4-methyl-cyclohexanecarbonyl)-phenyl-amino]-thiophene-2-carboxylic acid methyl ester.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08158675B2uspto-grants-2012_04