반응 #1755476

반응 방정식

methyl 5-nitro-2-furoate

hydrogen

→

methyl 5-amino-2-furoate

용매

EtOAc

반응 조건

후처리

1. 1
   여과the mixture was filtered through a celite pad
2. 2
   농축concentrated

실험 절차

A solution of 100 mg of methyl 5-nitro-2-furoate (Lancaster Synthesis, Windham, N.H., USA) in 20 ml of EtOAc was stirred with 20 mg of Pd/C (10%) under one atmospheric pressure of hydrogen gas. After at RT for 2 hours, the mixture was filtered through a celite pad and concentrated. Pure methyl 5-amino-2-furoate was obtained by purification on a fresh silica gel column eluted with 30% EtOAc in hexane.

출처