반응 #1738986

반응 방정식

methyl 4-hydroxy-4[3,4-(methylenedioxy)phenyl]-2-butynoate

→

methyl 3-[3,4-(methylenedioxy) benzoyl)-propiolate

용매

methylene chloride

methylene chloride

반응 조건

후처리

1. 1
   여과filtered over magnesium sulphate
2. 2
   농축concentrated
3. 3
   기타Crystallization of the residue from ether/hexane

실험 절차

A solution cf 7.3 g (31 mmol) of methyl 4-hydroxy-4[3,4-(methylenedioxy)phenyl]-2-butynoate in 80 ml of methylene chloride was added dropwise at 0° to a suspension of 77 g (0.89 mol) of manganese dioxide in 150 ml of methylene chloride. The reaction mixture was stirred at 0° for 30 minutes, filtered over magnesium sulphate and concentrated. Crystallization of the residue from ether/hexane yielded methyl 3-[3,4-(methylenedioxy) benzoyl)-propiolate of melting point 95°-97°.

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