반응 #171578

반응 방정식

1,1′-Thiocarbonyldiimidazole

N-phenylethylenediamine

DCM

→

title compound 301

수율 35.3%

1-phenylimidazolidine-2-thione

수율 35.3%

용매

THF

반응 조건

후처리

1. 1
   세척the solution was washed with 1N HCl
2. 2
   건조dried over anhydrous sodium sulfate
3. 3
   농축concentrated under reduced pressure

실험 절차

1,1′-Thiocarbonyldiimidazole (4.51 g, 25.3 mmol) was added to a solution of N-phenylethylenediamine (3 mL, 23.02 mmol) in THF (230 mL) and the mixture was stirred for 2 h at room temperature. DCM was added and the solution was washed with 1N HCl, dried over anhydrous sodium sulfate and concentrated under reduced pressure affording title compound 301 (1.45 g, 8.13 mmol, 35.3% yield). m/z: 179.1 (M+H)+

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