반응 #1714184

반응 방정식

sodium acetate

4-methyl-3-nitrobenzaldehyde

hydroxylamine hydrochloride

ethanol

→

5-hydroxyiminomethyl-2-methylnitrobenzene

수율 84.6%

용매

water

반응 조건

후처리

1. 1
   추출The reaction mixture was extracted with water and ethyl acetate
2. 2
   건조The organic layer was dried over anhydrous sodium sulfate
3. 3
   농축concentrated under reduced pressure

실험 절차

To a mixture of 4-methyl-3-nitrobenzaldehyde (3.00 g), hydroxylamine hydrochloride (1.64 g), ethanol (30 mL) and water (15 ml) was added sodium acetate (2.24 g) at room temperature, and then the mixture was stirred at room temperature for 1 hour. The reaction mixture was extracted with water and ethyl acetate. The organic layer was dried over anhydrous sodium sulfate, and concentrated under reduced pressure to obtain 5-hydroxyiminomethyl-2-methylnitrobenzene (2.77 g).

출처