반응 #1707704

반응 방정식

4-thioxo-1,3-thiazolidin-2-one

2-(2-methoxyethoxy)ethanamine

→

title compound

수율 84.4%

4-{[2-(2-methoxyethoxy)ethyl]amino}-1,3-thiazol-2(5H)-one

수율 84.4%

용매

ethanol

반응 조건

후처리

1. 1
   기타The solvent was evaporated under reduced pressure
2. 2
   기타the residue was purified by silica gel column chromatography (ethyl acetate)

실험 절차

To a solution of 4-thioxo-1,3-thiazolidin-2-one (2.24 g) in ethanol (20 mL) was added 2-(2-methoxyethoxy)ethanamine (2.5 g), and the mixture was stirred at room temperature for 5 hr. The solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate) to give the title compound (3.1 g).

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