반응 #170678

반응 방정식

water

3-aminopyrazole

2,5-hexanedione

→

titled compound

3-(2,5-Dimethylpyrrol-1-yl)-1H-pyrazole

용매

acetic acid

반응 조건

후처리

1. 1
   온도at reflux
2. 2
   여과the precipitated solid was collected by filtration
3. 3
   세척The resulting solid was washed with water (1000 ml)
4. 4
   기타dried under reduced pressure

실험 절차

To a solution of 3-aminopyrazole (100 g) in acetic acid (1000 ml) was added 2,5-hexanedione (148 ml), and the mixture was stirred for 2.4 hours at reflux. This reaction solution was cooled to room temperature, water (1000 ml) was added thereto, and the precipitated solid was collected by filtration. The resulting solid was washed with water (1000 ml), and dried under reduced pressure to give the titled compound (183 g).

출처