반응 #170525
ord-9d263cc8f5dd4575b47626a5887d6d94
반응 방정식
6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid
L-phenylalanine methylester hydrochloride
→
title compound
수율 88.0%
(S)-2-{[6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridine-3-carbonyl]-amino}-3-phenyl-propionic acid methyl ester
수율 88.0%
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (111 mg, 0.36 mmol) was converted, using L-phenylalanine methylester hydrochloride instead of 2-aminoethyl isopropylether, to the title compound (148 mg, 88%) which was obtained as a white solid. MS: m/e=470.1 [M−H]−.