반응 #170501

반응 방정식

6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid

rac-2-amino-1-propanol

→

title compound

수율 89.0%

N-(2-Hydroxy-1-methyl-ethyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide

수율 89.0%

반응 조건

실험 절차

As described for example 8b, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (150 mg, 0.5 mmol) was converted, using rac-2-amino-1-propanol instead of methylamine, to the title compound (158 mg, 89%) which was obtained as a white solid. MS: m/e=368.2 [M+H]+.

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