반응 #170410

ord-329a316aeb6e468480d3a8ca0560ae0c

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

As described for example 105, 6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid (99 mg, 0.33 mmol) was converted, using isopropylamine instead of 2,2,2-trifluoroethylamine, to the title compound (87 mg, 79%) which was obtained as an off white solid. MS: m/e=370.0 [M+H]+.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08846719B2uspto-grants-2014_09