반응 #170166

반응 방정식

Thionyl chloride

3-(2-thienyl)propanol

→

title compound

2-(3-Chloropropyl)thiophene

용매

THF

반응 조건

후처리

1. 1
   농축concentrated to dryness

실험 절차

Thionyl chloride (420 μL, 5.7 mmol) was added to a solution of 3-(2-thienyl)propanol (682.0 mg, 4.8 mmol) in THF (3 mL) at room temperature. The reaction mixture was stirred at 50° C. for 2 hours and then concentrated to dryness to afford the title compound as a brown oil. The product was used in the next step without further purification.

출처