반응 #1699807

반응 방정식

4,4-di(p-fluorophenyl)butylamine

3-bromopropionic acid ethyl ester

potassium carbonate

→

3-[4,4-di(p-fluorophenyl)-butylamino]-propionic acid ethyl ester

용매

2-butanone

반응 조건

후처리

1. 1
   여과The reaction mixture is filtered
2. 2
   농축the filtrate is concentrated by evaporation under reduced pressure

실험 절차

26.1 g (0.1 mol) of 4,4-di(p-fluorophenyl)butylamine and 18.1 g of 3-bromopropionic acid ethyl ester are refluxed with 21.0 g of potassium carbonate in 200 ml of 2-butanone for 24 hours while stirring. The reaction mixture is filtered and the filtrate is concentrated by evaporation under reduced pressure, yielding crude 3-[4,4-di(p-fluorophenyl)-butylamino]-propionic acid ethyl ester in the form of an oil.

출처