반응 #168902

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4-(3-aminophenylthio)-N-(4-morpholinophenyl)pyrimidin-2-amine

cyanoacetic acid

→

product

수율 65.5%

N-(3-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)-2-cyanoacetamide

수율 65.5%

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실험 절차

In a procedure analogous to Example 15, reaction of 4-(3-aminophenylthio)-N-(4-morpholinophenyl)pyrimidin-2-amine (50 mg, 0.13 mmol) and cyanoacetic acid (23 mg, 0.26 mmol) furnished the product (38 mg, 64%).

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