반응 #1687619

반응 방정식

3-Cyanopyridine

methyl iodide

methyl iodide

→

title compound

수율 81.0%

3-Cyano-1-methylpyridinium Iodide

수율 81.0%

용매

acetone

반응 조건

후처리

1. 1
   여과The mixture was filtered
2. 2
   세척the solid product was washed with acetone (100 ml)
3. 3
   기타After drying

실험 절차

3-Cyanopyridine (1) (104 g, 1 mol) and methyl iodide (150 g, 1.06 mol) in acetone (500 ml) was stirred for 5 hours at room temperature. Then more methyl iodide (20 g, 0.14 mol) was added, and the reaction mixture was stirred overnight at room temperature. The mixture was filtered and the solid product was washed with acetone (100 ml) and then thoroughly with ether. After drying, 199 g (0.81 mol, 81%) of the title compound were obtained, M.P. 145°-150° C.

출처