반응 #1686194

ord-6bdd92db397c4d1d8ed9732aa417b23d

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타was hydrogenated at 100° C.
  2. 2
    온도to cool
  3. 3
    여과The catalyst was filtered
  4. 4
    기타was removed in vacuo from a small portion of the solution
  5. 5
    기타to give a product

실험 절차

4,4'-Dinitro-2-hydroxybenzanilide (20.0 g, 0.066 mol), dioxane (300 mL), and 10 percent Pd/C were placed in a 600 mL Hastelloy C Parr Reactor. The material was hydrogenated at 100° C. and 150 psi (1033 kPa) of hydrogen for 16 hours, after which the reactor was allowed to cool and hydrogen was vented off. The catalyst was filtered and the major portion of the solution was set aside for Step C, while dioxane was removed in vacuo from a small portion of the solution to give a product having a melting point of 235° C. to 238° C.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05739344uspto-grants-1998_04