반응 #1668370

ord-d70ab79837ac4668a58b5d4e01dbea56

반응 방정식

CC1(C)CCNC1
CC1(C)CCNC1
CC(Cl)c1cccnc1
CC(Cl)c1cccnc1
→
CC(c1cccnc1)N1CCC(C)(C)C1
CC(c1cccnc1)N1CCC(C)

반응물

CC1(C)CCNC1
CC1(C)CCNC1
CC(Cl)c1cccnc1
CC(Cl)c1cccnc1

시약

O=C([O-])[O-].[Cs+].[Cs+]
cesium carbonate
[I-].[K+]
potassium iodide

용매

CN(C)C=O
dmf
CN(C)C=O
DMF
CN(C)C=O
DMF

반응 조건

온도
70°CELSIUS

후처리

  1. 1
    workup.ALIQUOT
  2. 2
    workup.ADDITIONDilution of the aliquot (2 uL) with DMSO (200 uL).

출처

DOI: 10.1016/j.chempr.2024.04.001Fig 7 data from Golden paper