반응 #165752

반응 방정식

3-amino-N′-(benzoyloxy)-6-bromopyrazine-2-carboximidamide

→

resultant product

수율 87.0%

5-bromo-3-(5-phenyl-1,2,4-oxadiazol-3-yl)pyrazin-2-amine

수율 87.0%

용매

water

반응 조건

후처리

1. 1
   기타quenched with NaHCO3

실험 절차

A mixture of 3-amino-N′-(benzoyloxy)-6-bromopyrazine-2-carboximidamide (575 mg, 1.711 mmol) and polyphosphonic acid (2.300 mL) was heated at 70° C. for 3.5 hours. The resultant solution was diluted with water (20 mL), quenched with NaHCO3 and the resultant product isolated by filtration (475 mg, 87% Yield) as a fawn solid.

출처