반응 #164517

ord-d15c03bb3ed448518e68877c302ddfdf

반응 방정식

CC1(C)SCCN[C@H]1C(=O)O
(S)-2,2-dimethyl-thiomorpholine-3-carboxylic acid
O=S(=O)(Cl)c1ccc2ccccc2c1
naphthalene-2-sulfonyl chloride
→
CC1(C)SCCN(S(=O)(=O)c2ccc3ccccc3c2)C1C(=O)O
title compound
CC1(C)SCCN(S(=O)(=O)c2ccc3ccccc3c2)C1C(=O)O
2,2-Dimethyl-4-(naphthalene-2-sulfonyl)-thiomorpholine-3-carboxylic acid

반응물

CC1(C)SCCN[C@H]1C(=O)O
(S)-2,2-dimethyl-thiomorpholine-3-carboxylic acid
O=S(=O)(Cl)c1ccc2ccccc2c1
naphthalene-2-sulfonyl chloride

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Following typical sulfonylation conditions and method L, the title compound is prepared from (S)-2,2-dimethyl-thiomorpholine-3-carboxylic acid and naphthalene-2-sulfonyl chloride. LCMS (m/z): 381.2 (M+1), 379.3 (M−1), CHN: Calc CHN: 53.66, 5.30, 7.36. Found CHN: 593.51, 5.20, 7.07.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08841291B2uspto-grants-2014_09