반응 #163669

반응 방정식

N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine

2,4-dichloro-5-methylpyrimidine

3-hydroxyaniline

→

N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine

반응 조건

실험 절차

In a manner analogous to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,4-dichloro-5-methylpyrimidine with 3-hydroxyaniline gave N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine. LCMS: ret. time: 16.76 min.; purity: 100%, MS (m/e): 309 (MH+).

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