반응 #163525

반응 방정식

THF

pentafluorobenzoyl chloride

NaH

oxazinone

→

2-ethyl-4-(perfluorophenylcarbonyl)-8-(prop-1-enyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

수율 63.0%

반응 조건

후처리

1. 1
   기타240 mg of P5 were obtained

실험 절차

Procedure & NMR Data: 265 μL of pentafluorobenzoyl chloride (2 eq, 1.84 mmol) was added to a mixture of 148 mg of NaH (4 eq, 3.68 mmol) and 200 mg (0.92 mmol) of oxazinone P2 in THF (22 ml). 240 mg of P5 were obtained, yield 63%.

출처