반응 #162961
ord-53f4d7ff59f245f59e1bfcfa30d2f0b4
반응 방정식
KBr
3-(4-amino-phenyl)-isoxazol-5-carboxylic acid ethyl ester
cyclohexyl isocyanate
3-[4-(3-phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester
→
title compound
수율 75.0%
3-[4-(3-cyclohexyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester
수율 75.0%
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타was obtained in 75% yield
실험 절차
The title compound was prepared from 3-(4-amino-phenyl)-isoxazol-5-carboxylic acid ethyl ester and cyclohexyl isocyanate by same procedure as set forth for the preparation of 3-[4-(3-phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester and was obtained in 75% yield. Mass (ES+), 358 (M++1); IR (KBr): 3304, 2928, 2852, 1731, 1634, 1570 (br); 1H NMR (DMSO-d6) δ: 1.33 (t, 3H), 1.14-1.81 (4×m, 10H), 3.45 (br, 1H), 4.37 (q, 2H), 6.18 (d, 1H), 7.50 (d, 2H), 7.60 (s, 1H), 7.79 (s, 1H), 7.8.1 (d, 2H), 8.59 (s, 1H).