반응 #162886

ord-18129cb107d14d8aa796bd853e2926c2

반응 방정식

c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
Intermediate 26
c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
N-(1H-indazol-5-yl)-2-azabicyclo[2.2.2]octan-4-amine
COc1cccc(C=O)c1
3-methoxybenzaldehyde
→
COc1cccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2CC3)c1
title compound
COc1cccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2CC3)c1
N-(1H-indazol-5-yl)-2-(3-methoxybenzyl)-2-azabicyclo[2.2.2]octan-4-amine

반응물

c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
Intermediate 26
c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
N-(1H-indazol-5-yl)-2-azabicyclo[2.2.2]octan-4-amine
COc1cccc(C=O)c1
3-methoxybenzaldehyde

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Reaction of Intermediate 26 with 3-methoxybenzaldehyde affords the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08835457B2uspto-grants-2014_09