반응 #162884

ord-1f6957870d9442cab408ce1679e806f3

반응 방정식

c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
Intermediate 26
c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
N-(1H-indazol-5-yl)-2-azabicyclo[2.2.2]octan-4-amine
Cc1ccc(C=O)cc1
4-methylbenzaldehyde
→
Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2CC3)cc1
title compound
Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2CC3)cc1
N-(1H-indazol-5-yl)-2-(4-methylbenzyl)-2-azabicyclo[2.2.2]octan-4-amine

반응물

c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
Intermediate 26
c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2
N-(1H-indazol-5-yl)-2-azabicyclo[2.2.2]octan-4-amine
Cc1ccc(C=O)cc1
4-methylbenzaldehyde

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Reaction of Intermediate 26 with 4-methylbenzaldehyde affords the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08835457B2uspto-grants-2014_09