반응 #162883

ord-61993622c6a044cd927ec6799c03abe0

반응 방정식

c1cc2[nH]ncc2cc1NC12CCC(C1)NC2
Intermediate 25
c1cc2[nH]ncc2cc1NC12CCC(C1)NC2
N-(2-azabicyclo[2.2.1]heptan-4-yl)-1H-indazol-5-amine
Cc1ccc(C=O)cc1NS(C)(=O)=O
N-(5-formyl-2-methylphenyl)methanesulfonamide
→
Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2C3)cc1NS(C)(=O)=O
title compound
Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2C3)cc1NS(C)(=O)=O
N-(5-((-4-((1H-indazol-5-yl)amino)-2-azabicyclo[2.2.1]heptan-2-yl)methyl)-2-methylphenyl)methanesulfonamide

반응물

c1cc2[nH]ncc2cc1NC12CCC(C1)NC2
Intermediate 25
c1cc2[nH]ncc2cc1NC12CCC(C1)NC2
N-(2-azabicyclo[2.2.1]heptan-4-yl)-1H-indazol-5-amine
Cc1ccc(C=O)cc1NS(C)(=O)=O
N-(5-formyl-2-methylphenyl)methanesulfonamide

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Reaction of Intermediate 25 with N-(5-formyl-2-methylphenyl)methanesulfonamide affords the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08835457B2uspto-grants-2014_09