반응 #162265

반응 방정식

methacrylate ester

7-Tert-butoxycarbonyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furane-6-yl Methacrylate

→

intended product

수율 81.0%

6-Methacryloyloxy-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furane-7-carboxylic Acid

수율 81.0%

용매

formic acid

반응 조건

후처리

1. 1
   기타obtained in Synthesis Example 1-1-1
2. 2
   기타After formic acid was removed by distillation under reduced pressure, recrystallization

실험 절차

Dissolved into 810 g of formic acid was 202.2 g of the methacrylate ester (25) obtained in Synthesis Example 1-1-1; and then, the resulting mixture was stirred at 25° C. for 16 hours. After formic acid was removed by distillation under reduced pressure, recrystallization was made from ethyl acetate to give 135.1 g of the intended product (Yield 81%).

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