반응 #161766

ord-c07db21c58be42b78949ab930e4c0d28

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타evaporated down
  2. 2
    기타The product was reacted without further purification

실험 절차

0.29 g (1.1 mmol) methyl 2-chloro-6-methanesulphonylamino-isonicotinate in 5.0 mL tetrahydrofuran and 1 mL water were mixed with 79 mg (3.3 mmol) lithium hydroxide and stirred overnight at RT. The reaction mixture was acidified with 1M aqueous hydrochloric acid and evaporated down. The product was reacted without further purification.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08829006B2uspto-grants-2014_09