반응 #161700

반응 방정식

hydrochloric acid

cyclobutanecarboxylic acid chloride

phenylhydrazine

pyridine

→

Cyclobutanecarboxylic acid N′-phenylhydrazide

용매

DMF

반응 조건

후처리

1. 1
   여과filtered
2. 2
   세척washed with 50 mL water
3. 3
   기타dried i
4. 4
   추출The product was extracted with 50 mL ether and suction
5. 5
   여과filtered
6. 6
   세척The solid was washed with 20 mL ether
7. 7
   기타dried in the air

실험 절차

3.54 mL (31.0 mmol) cyclobutanecarboxylic acid chloride were added dropwise at RT to 3.00 mL (30.2 mmol) phenylhydrazine and 4.75 mL (60.0 mmol) pyridine in 30 mL DMF. The mixture was stirred for 1 h at RT and poured onto 200 mL of a 1M hydrochloric acid solution. The precipitated solid was suction filtered, washed with 50 mL water and dried i. vac. The product was extracted with 50 mL ether and suction filtered. The solid was washed with 20 mL ether and dried in the air.

출처